Next, the swelling or inflammation will likely spread. Inflammation is a key sign of immune activity, and will often signal an allergic reaction. The eyes, lips, hands, feet, and other areas of the face and body may swell up rapidly. Some people’s eyes swell shut, or their lips may double in size.
Whenever body parts swell up, they may also itch and tingle. Itchy, swollen eyes, for instance, are common in an anaphylactic reaction.